The Pharmacogenomics Knowledgebase (PharmGKB) is an integrated online knowledge resource for the understanding of how genetic variation contributes to variation in drug response. PharmGKB is an NIH-funded resource that provides information about how human genetic variation affects response to medications. - PharmGKB PharmGKB - PubChem data source information. Find all the data submitted to PubChem by PharmGKB. PharmGKB captures pharmacogenomic relationships in a structured format so that it can be searched, interrelated, and displayed according to the researchers interests, either for manual inspection or to download for further analyses. The evolution of PharmGKB + CPIC ClinPGx is a comprehensive clinical pharmacogenomic (PGx) resource created to support and expand PGx knowledge, implementation and education. It integrates the PharmGKB, CPIC and PharmCAT projects, with additional features and content. PharmGKB pathways are evidence-based diagrams detailing the pharmacokinetics (PK) or pharmacodynamics (PD) of a PGx-relevant drug, accompanied by text providing background on the drug and a discussion of its PK, PD and PGx. If you’re looking to dig deeper into the science of pharmacogenomics, the PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including clinical guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships. PharmGKB is a registered trademark of HHS and is financially supported by NIH/NHGRI/NICHD/NIDA/NCI. PharmGKB is managed at Stanford University (U24HG010615). ©2001- 2026. e.g., human; SARS-CoV-2; lncRNA; single cell; spatial omics; immune; Oryza sativa; European Bioinformatics Institute; China The Pharmacogenomics Knowledgebase (PharmGKB) is a resource that collects, curates, and disseminates information about the impact of human genetic variation on drug responses.